A.M. Brufsky, M. Mayer, H.S. Rugo, M. Ulcickas Yood, P.A. Kaufman, E. Tan-Chiu, D. Tripathy, M. Birkner, L. Wang,
M.G. Brammer, D.A. Yardley RegistHER: Patient Characteristics and Time Course of Central Nervous System Metastases in Patients with HER2+ Metastatic Breast Cancer. ASCO Breast Cancer 2008 Sept 5-7.
Heyn, C., Ronald, J.A., Ramadan, S. S., MacKenzie, L.T., Mikulis, D.J., Palmieri, D., Bronder, J.L., Steeg, P.S., Yoneda, T., MacDonald, I.C., Chambers, A.F., Rutt, B.K. and Foster, P.J.: In vivo tracking of growth and dormancy of solitary cells in a mouse model of breast cancer metastasis to the brain using MRI. Mag. Reson. Med. 56: 1001-1010, 2006.
Mayer, M.: A patient perspective on brain metastases in breast cancer. Clin. Cancer Res. 13: 1623-1624, 2007.
Muldoon LL, Soussain C, Jahnke K, Johanson C, Siegal T, Smith QR, Hall WA, Hynynen K, Senter PD, Peereboom DM, Neuwelt EA: Chemotherapy delivery issues in central nervous system malignancy: a reality check. J Clin Oncol. 25(16):2295-305, 2007.
Palmieri, D., Smith, Q.R., Lockman, P.R., Bronder, J.L., Gril, B., Ahmad, A., Chambers, A.F., Weil, R. J. and Steeg, P.S.: Brain metastasis of breast cancer. Breast Diseases. 26:139-147, 2007.
Palmieri, D., Chambers, A.F., Felding-Haberman, B., Huang, S. and Steeg, P.S.: The biology of metastasis to a sanctuary site. Clin. Cancer Res. 13: 1656-1662, 2007.
Palmieri, D., Bronder, J.L., Herring, J.M., Yoneda, T., Weil, R.J., Stark, A.M., Kurek, R., Vega-Valle, E., Feigenbaum, L., Vortmeyer, A.O., Aldape, K. and Steeg, P.S.: Her-2 overexpression increases the metastatic outgrowth of breast cancer cells in the brain. Cancer Res. 67:4190-4198, 2007.
Brogi, E., Murray, M.P., Nehhozina, T., Akram, M., Cranor, M., Seidman, A. Clinical and pathologic characteristics of brain metastases of breast carcinoma: A study of 74 patients. San Antonio Breast Cancer Symposium, San Antonio, TX. 2006.
Fitzgerald Daniel, Palmieri Diane, Vega-Valle, Jeanne Herring, Steeg Patricia. A xenograft model of brain metastasis of breast cancer: metastatic tumors and the brain microenvironment. American Association of Cancer Research Annual Meeting.Los Angeles, CA. 2007
Gril Brunhilde, Palmieri Diane, Elezar Vega-Valle, Hua k., Herring Jeanne, Gilmer Tona, Rubin Stephen, Steeg Patricia. Lapatinib Prevents the Metastatic Colonization of EGFR+ and Her-2+ Breast Cancer Cells in the Brain. American Association of Cancer Research Annual Meeting. Los Angeles, CA. 2007.
Heyn C, Ronald JA, Ramadan SS, Snir JA, Barry AM, MacKenzie LT, Mikulis DJ, Palmieri D, Bronder JL, Steeg PS, Yoneda T, MacDonald IC, Chambers AF, Rutt BK, Foster PJ. In vivo tracking of growth and dormancy of solitary cells in a mouse model of breast cancer metastasis to brain using MRI. 14th Scientific Meeting & Exhibition of the International Society for Magnetic Resonance in Medicine, Seattle,WA. 2006.
Hunt Mathew, Muldoon Leslie, Palmieri Diane, Steeg Patricia, Neuwelt Edward. âHER-2 status influences survival in a rat model of brain metastasis from breast cancerâ. Annual Blood-Brain Barrier Consortium Meeting. Skamania Lodge, WA. 2007.And American Association of Cancer Research Annual Meeting. Los Angeles, CA. 2007.
Mittapalli RK, Manda VK, Smith QR and Lockman PR. Permeability of the fluorophore Texas red is not subject to MRP-2 mediated efflux at the blood-brain barrier. The American Association of Pharmaceutical Scientists, Annual Meeting. San Diego, CA. 2007.
Mittapalli RK, Fitzgerald A, Manda VK and Lockman PR. A computational approach to predict the blood-brain permeability of fluorescent dyes. The American Association of Pharmaceutical Scientists, Annual Meeting. San Diego, CA. 2007.
Newsham Irene and Price Janet. Dissecting the extravasation process of metastatic breast cancer cells using an Electric Cell- Substrate Impedance Sensing (ECIS) assay. Metastasis Research Society Meeting, 2006.
Palmieri Diane, Bronder Julie, J. Weil Robert, Stark Andreas, Davis Sean, Vega-Valle Eleazar, Herring Jeane, Toshiyuki Yoneda, Kurek Raffael, Mehdorn H., Meltzer Paul, Steeg Patricia. Preclinical studies in support of the use of Vorinostat (SAHA) for the treatment of brain metastases of breast cancer. American Association of Cancer Research Annual Meeting. Los Angeles, CA. 2007
Ramadan S, Heyn C, Rutt B, Foster P. Single cell MRI with FIESTA:quantitative benefits of 3T vs. 1.5T. 14th Scientific Meeting & Exhibition of the International Society for Magnetic Resonance in Medicine, Seattle, WA. 2006.
Ramadan S, MacKenzie L, Steeg P, Palmieri D, Chambers A, Rutt B, Foster P. In-vivo MR tracking of solitary cells as a tool for comparing the metastatic behaviour of two distinct breast cancer cell lines. Imaging Network Ontario 6th Imaging Symposium, Toronto, ON, Canada. 2007.
Ramadan SS, MacKenzie LT, Steeg PS, Chambers AF, Rutt BK, Foster PJ. In vivo tracking of solitary cells as a tool for comparing the behaviour of two metastatically-distinct cell lines in a mouse model of breast cancer metastasis to the brain. 15th Scientific Meeting & Exhibition of the International Society for Magnetic Resonance in Medicine, Berlin, Germany. 2007.
Rudraraju Thomas V, Lockman PR, and Smith QR. Blood brain barrier permeability and transport of temozolomide. The American Association of Pharmaceutical Scientists, Annual Meeting. San Diego, CA. 2007.
Taskar K, Mittapalli RK, Rudraraju V, Egbert JA, Bohn KA, Gaasch JA, Thomas F, Lockman PR and Smith QR. Improved Left Ventricle Intracardiac injection method for brain metastases of breast cancer in immune compromised mice. Society for Neuroscience Annual Meeting. San Diego, CA. 2007
8th Annual Symposium of the MIT Koch Institute for Integrative Cancer Research, Applied Biosystems/Life Technologies Leadership in Oncology Lecture, Boston, MA. âMonitoring the fate of cancer cells during metastasisâ. June 19, 2009.
7th International Symposium on Minimal Residual Cancer, Athens, Greece. âImaging experimental models of metastasis and dormancyâ. September 17, 2009.
European Commission Workshop on Trends in Translational Cancer Research, Bergen, Norway.âDoes tumour dormancy offer therapeutic strategies?â September 29, 2009
The 2010 Miami Winter Symposium, Miami, FL. âMetastatic Inefficiency and Tumor Dormancyâ. February 22, 2010.
American Association for Cancer Research Annual Meeting, Washington, DC. âExperimental studies of Tumor Metastasis and Clinical Implicationsâ. Plenary speaker. April 21, 2010.
MSKCC Brain Tumor Seminar Series, Memorial Sloan-Kettering Cancer Center, New York, NY. âImaging of experimental models of brain metastasisâ. May 3, 2010.
The Prostate Centre at Vancouver General Hospital, Vancouver, BC. âTumor metastasis: Experimental studies and clinical implicationsâ. May 14, 2010.
Imaging Cancer. Relay for Life, Canadian Cancer Society, St. Catharines, ON, Canada: June 19, 2009.
Suyun Huang: Transcriptional Regulation of Tumor Growth and Metastases, Emory Winship Elkin lecture series, Winship Cancer Institute, Emory University School of Medicine Atlanta, GA, 3/2010
Leslie L. Muldoon, Ph.D. âPre-clinical studies of iron oxide nanoparticles as CNS imaging agentsâ Presented at the annual Blood-Brain Barrier Consortium meeting, March 2010, Sun River OR.
Leslie L. Muldoon, Ph.D. âVascular effects of an anti-integrin antibody in a rat brain tumor modelâ AACR Neuro-tumor club presentation, Washington DC, April 2010.
Leslie L. Muldoon, Ph.D., and Edward A. Neuwelt, MD. âAntibody-targeted therapy in rat brain tumor modelsâ DOD COE annual meeting, September 2009, Bodega Bay CA.
Patricia Steeg and Diane Palmieri:
Stephan Woditschka, "Molecular Targets for the Prevention of Breast Cancer Brain Metastases", Cancer Prevention Fellowship Program, Fellows Research Meeting, June 2nd, 2010, Rockville, MD.
AACR Annual Meeting Educational Session, Brain Metastases, Patricia Steeg
Patricia Steeg 5-15-10 3rd Annual Jean Sindab Triple-Negative Breast Cancer Symposium, Brain Metastases of breast cancer.
Patricia Steeg, 3-26-10 Keynote Lecture, Huggins Research Conference, University of Chicago, âBrain metastasis of breast cancerâ.
Patricia Steeg 3-5-10, Wake Forest University, âBrain metastasis of breast cancerâ.
Patricia Steeg, 10-4-09, Radiation Research Society, invited talk âBrain metastasis of breast cancerâ. Savannah, GA
Diane Palmieri, ASCO, Meet the Professor, 2009
Brunilde Gril, Molecular mechanism of brain metastasis in ErbB2+ breast cancer. âErbB2+ driven breast cancer: Old and New.â May 1, 2009 (Taipei, Taiwan), Taiwan Joint cancer conference and GlaxoSmithKline
Brunilde Gril, Molecular mechanism of cancer metastasis Meet-the-Expert Session, âErbB2+driven breast cancer: Old and New.â May 1, 2009 (Taipei, Taiwan), Taiwan Joint cancer conference and GlaxoSmithKline
Brunilde Gril, Molecular events in breast cancer progression Breast Cancer Workshop: Molecular Pathobiology of Breast Cancer Experimental Biology, FASEB Meeting, April 24-28, 2010 (Anaheim, California, US)
Quentin Smith and Paul Lockman:
Quentin Smith, Invited Speaker and Session Chair (June, 2009), 8th International Cerebral Vascular Biology Conference, Sendai, Japan, âRole of active efflux transporter, passive permeability, and parenchymal binding on brain metastasis uptake and distribution of anticancer agents.â
Kunal Taskar (Graduate Student in Smith lab), Invited Speaker (June, 2009), 8th International Cerebral Vascular Biology Conference, Sendai, Japan, âBlood-brain barrier permeability and active efflux transport of drugs used in the treatment of metastatic breast
Lockman PR. Does Chemotherapy Reach Effective Concentrations for the Treatment of Brain Metastases of Breast Cancer? Medical Rounds â London Health Sciences Center. Invited Seminar and Discussion. London Ontario, Canada. (February, 2010)
Lockman PR. Are the Blood-Brain and Blood-Tumor Barriers an Impediment to Drug Delivery? Canadian Institute of Health Research -- Strategic Training Program in Cancer Research & Technology. Translational Seminar Series. Invited Seminar London Ontario Canada (February, 2010)
Chambers Ann, âDormancy and Growth of Tumor Cells in Ectopic Sitesâ. Invited speaker, Educational Session on âInvasion and Metastasisâ. American Association for Cancer Research 97th Annual Meeting, Washington, DC, April 2006.
Chambers Ann, âBiology of Tumor Metastasis and Clinical Implicationsâ. Invited speaker, McGill Cancer Group Seminar Series, McGill University, Montreal, Quebec, Canada, April 2006.
Chambers Ann, âTumor Metastasis: Mouse Models and Preclinical Imagingâ. Invited speaker, Lawson Imaging Seminar Series, London, Ontario, Canada. April 2006.
Chambers Ann, âBreast Cancer Metastasisâ. Invited speaker, EMBO Conference on Common Molecular Mechanisms of Mammary Gland Development and Breast Cancer Progression. Dublin, Ireland. June 2006.
Ann Chambers, âImaging the metastatic process in experimental models and clinical simplicationsâ. Invited workshop participant, National Cancer Institutes, NIH, âTumor Dormancy Workshopâ. Bethesda, MD. July 2006.
Chambers Ann, âImaging the Metastatic Process: Preclinical Models and Clinical Implicationsâ. Invited speaker, Usha Mahajani Symposium on Cancer Biology, University of California San Diego/Salk Institute, La Jolla, CA, September 2006.
Chambers Ann, âImaging the Metatatic Process in Experimental Models and Clinical Implicationsâ. Invited Speaker, Ben May Institute for Cancer Research, University of Chicago. Cancer Research Symposium on Frontiers in Metastasis Research, Chicago, October 2006.
Chambers Ann, âBiology of Breast Cancer Metastasisâ. Invited speaker/faculty, 7th Annual New Strategies in Breast Cancer Conference. Philadelphia, PA. April 2007.
Chambers Ann, âHost factors in tumor dormancyâ. Invited speaker, 1st Annual Columbus Breast Cancer Symposium. Columbus, OH. April 2007.
Chambers Ann, âImaging tumor metastasis and dormancy in experimental modelsâ. Invited speaker, Second International Symposium on Cancer Metastasis and the Lymphovascular System, San Francisco, CA. May 2007.
Chambers Ann and Nathanson David, âAnimal models to study lymphatic and vascular metastasisâ. Meet-the-Professor Breakfast, Second International Symposium on Cancer Metastasis and the Lymphovascular System, San Francisco, CA. May 2007.
Chambers Ann, âNovel imaging approaches for studying tumor metastasisâ. Invited participant, Fondation IPSEN annual meeting on Cancer Science, Metastasis and Invasion. Cancer think-tank. Abazzia de Spineto, Tuscany, Italy. May 2007.
Lockman Paul, âDrug delivery across the blood-tumor barrier.â Invited Seminar, The University of Texas, MD. Anderson Cancer Center, Cancer Biology Seminar Series. Houston, Tx. February, 2007.
Lockman Paul, âPermeability at the blood-tumor barrier.â Invited Seminar, Northeastern Ohio University, Colleges of Medicine, Akron, Ohio. 2007.
Neuwelt Edward, âImmunotherapy in Brain Tumors: Preclinical and Clinical Studiesâ Presented at the annual Blood-Brain Barrier Consortium meeting. Skamania, WA. 2007.
Neuwelt Edward, âMechanisms of Disease: The Blood-Brain Barrier and CNS Tumorsâ Henry Ford Hospital, Detroit MI. 2006.Copyright BrainMetsBC.orglogo
Smith Quentin, âTumors and the Blood-Brain Barrierâ 13th Annual Blood-Brain Barrier Consortium Meeting. Sevenson, WA. March 2007.
Smith Quentin, âBrain Drug Delivery through Carrier-Mediated Transportâ 18th Annual Spring Brain Conference. Sedona, Arizona.
Patricia Steeg, âA molecular portrait of breast cancer metastasis to the brainâ. Ruth Sager Memorial Lecture, Boston Cancer Research Association. April 2007.
Steeg Patricia, âBrain metastases of breast cancerâ. Keynote speaker, Ben May Institute for Cancer Research, University of Chicago. Cancer Research Symposium on Frontiers in Metastasis Research. October 2006.
Steeg Patricia, âThe role of Her-2 in brain metastasisâ. Invited speaker, BRESCOM Breast cancer and metastasis conference. Paris, France. June 2006.
Steeg Patricia, âNew molecular targets for metastatic breast cancerâ. Invited speaker, Metastatic Breast Cancer Network, New York, NY. October 2006.